Dr. Tanju YILDÖN & Tıp Bilim Eğitimi

İnflammasomes yani inflamazomlar


I-NLR-subset inflammasomes

a-NLRP1

            NLRP1B ve NLRP2 Bacillus anthracis lethal toxinİnde etkilidir.

b-NLRP3

c-NAIP/NLRC4

d-The Adaptor ASC, Pycard

II-AIM2, IFI16

a-AIM2 “Interferon-inducible protein AIM2”, “absent in melanoma 2”

b-IFI16 “Gamma-interferon-inducible protein Ifi-16 (Ifi-16)”

III-Pyrin

IV-Non-canonical inflammasomes

V-Epithelial inflammasomes

a-Epithelial NAIP/NLRC4

b-Epithelial non-canonical inflammasomes